A mesenchymal stem cell, or MSC, is an unspecialized cell that can develop into an osteoblast. ![]() Mesenchymal stem cells within mesenchyme or the medullary cavity of a bone fracture initiate the process of intramembranous ossification. Unlike endochondral ossification, which is the other process by which bone tissue is created during fetal development, cartilage is not present during intramembranous ossification. Transmission electron micrograph of a mesenchymal stem cell that is displaying typical ultrastructural characteristics. Intramembranous ossification is also an essential process during the natural healing of bone fractures and the rudimentary formation of bones of the head. Intramembranous ossification is one of the two essential processes during fetal development of the gnathostome (excluding chondrichthyans such as sharks) skeletal system by which rudimentary bone tissue is created. ![]() Mesenchymal bone development that forms the non-long bones
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